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https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/31facf23-5815-4411-a045-db7327df1b92/travis-faust-600px.webp NEWS - Congratulations to Travis for receiving an Alzheimer’s Association Research Fellowship for All! Travis was awarded Alzheimer's Association Research Grant to look at astrocyte-microglia interactions regulating synapse loss in Alzheimer's disease. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1694789815437-SL2HQEGD6ZRUVCCKKG0X/Melanie.JPG NEWS - Congratulations to Melanie for receiving F30 award from NIH! Melanie was awarded NIH Ruth L. Kirschstein National Research Service Award for MD/PhD students (F30) to study periventricular inflammation in MS. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/eab0dc78-94b5-4a97-8e71-5af1ee736376/2fcf2a32-2d9e-464c-887f-02013de1d046.png NEWS - Congratulations to Dori for receiving funding from Cure Alzheimer's Fund! A project studying ependymal cells, which are cells sitting between the cerebrospinal fluid and brain tissue, and their potential role as cellular conduits that initiate and propagate neuroinflammatory signals in the brain during Alzheimer’s disease. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/82b2de3b-f946-4119-ab7c-43b8a56135d1/IMG_5703.jpg NEWS - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1762979321437-EALTA4AD5C5H8852BQFP/IMG_5344.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1762979320377-Z2UYID4PRLEZJM7MZDO8/IMG_9354.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1762979322521-WAC0ZK8YIRBKEDYO45UP/IMG_9359.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1762979357144-O1LWOM7MHKDNVAXMREBQ/IMG_5341.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/216a5abd-4cbd-478e-9e84-3777323db8f1/NaomiFettig_Headshot_full.jpg NEWS - Welcome Naomi! The Schafer lab is lucky to have Naomi Fettig join our lab as a postdoctoral associate! She will focus on understanding microglia-T cell communication in demyelinating disease. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/d4515fa9-983f-4c99-b6dc-a7d3b02b7b14/IMG20250926124849+2.jpg NEWS - Farewell to Johana, our beloved lab manager https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/3b1b813a-50c9-4add-8951-bdf01cb21acf/10-07_schafer_and_faust-1320px.webp NEWS - Make it stand out Published in Cell, these findings are in an emerging area of interest for neurobiologists who want to understand how different cells in the brain interact to rewire the brain. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/6d7a73b7-52ae-40bc-9f4e-faf81c50b3dd/Screen+Shot+2025-09-10+at+11.45.39+AM.png NEWS - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/b265fdd5-8d81-4eeb-a2d1-cb96a005d203/07-07_riccio-schafer--thompson-4-1320x682px.jpg NEWS - Make it stand out Investigating a novel liver-brain axis driven by extracellular vesicles. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/c1030728-5a2a-42c6-97aa-0521311cd9ef/Sherman%2C+Delaney.jpg NEWS - Welcome Delaney! The Schafer lab was lucky to have Delaney Sherman join us as a research associate. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/bbed58da-66eb-4731-a554-413e98e6a3fe/IMG_6714.jpg NEWS - Farewell to Maggie and Rob, our beloved Research Associates! Rob is going to Hofstra Zucker School of Medicine to pursue his medical education. Maggie will begin working at a family care practice as a medical assistance. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/86a04a81-0e7d-43b4-83b8-a35bac2a7239/schafer-d.jpg NEWS - Congratulations to Dori for continuing to hold her endowed chair position! Dorothy P. Schafer, PhD, associate professor of neurobiology, who last year was appointed the inaugural holder of the UMass Chan Medical School Chair in Biomedical Research I, will continue to hold this endowed chair, now renamed the Molly McGovern Chair in Biomedical Research. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/bd809351-c4a5-4f72-aeb8-7af7d64abdd7/IMG_3320.jpg NEWS - Chun-Wei presented her work at Boston Interactive Glia Group (BIGG) meeting! Chun-Wei shared her project on “Neuronal subtype vulnerability to microglia-induced synapse loss” and got great feedback and generated inspiring discussions! https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1721679190587-FYXUS0U83X81FVAZZ5LY/IMG_8082.jpg NEWS - Congratulations to Anna! Cheers to Anna who passed her Qualifying Exam in April 2025. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/571477e0-f61c-44e3-9002-9dbfcb7cbdc6/image000000+3.jpg NEWS - Eva presented her work at Gordon Research Conference Glial Biology in March 2025 The research of astrocyte modulate a critical window of microglia-mediated synapse remodeling sparks exciting interest! https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/3fbda8f5-3999-4f82-a349-e5a24364889b/IMG_2925.jpg NEWS - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/34ed5f61-5a6b-499c-abd1-c4a1d827b156/Screen+Shot+2025-04-07+at+11.22.52+AM.png NEWS - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1742921187823-D586U6LTZYSIY9G8GSRJ/IMG_1041_2.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1742921199346-9KCI5GCIKZB9STHQ6INL/IMG_1914+3.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/82e44bed-63db-497a-8218-ada5715d3c61/IMG_2852.jpg NEWS - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/a00c4719-8e60-44e7-b5d0-f063a097b049/IMG_2859.jpg NEWS - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1d5c41b6-9c03-4abb-b0e9-e606ced2c18f/Screen+Shot+2024-11-08+at+4.40.08+PM.png NEWS - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1730497194222-UA88W09POQVCQ5D4ACPX/IMG_7445.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1730497198790-TTRCV8QMI8SN9O1NKD4J/IMG_6226.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1730497298975-SA36UTP7K5NODWSZ9EUV/IMG_1836.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1730497201295-00WWSVZAR8J7JWS5490A/IMG_6222.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1730497203575-4OR2RXVJ56YWMP7XV3PS/IMG_0651+%281%29.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1730497206107-L938OU6ZJMWMAX1DBI6J/IMG_6218.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/a17e7b78-d04a-45a9-adde-dd6ad04b4781/IMG_2418.jpg NEWS - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1730496569215-EFSKOLB7UVCGXTP74KMU/IMG_2412.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1730496570803-7C2TFA0L5PTVII34DJ7V/IMG_2408.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1730496573320-1LUC0CFBFN4SDHA4YQ9S/IMG_2406.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1730496575062-R11G7JKFLPG1OZDDQ89P/IMG_2404.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/4976fe5d-183e-4f94-864e-baf4cd9dd24e/_D608822.JPG NEWS - Congratulations to Melanie and Echo! Cheers to Melanie and Echo who passed their Qualifying Exam in the Academic Year 2023-24. They were recognized for their progression into doctoral candidacy. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/0adb79e5-6cd3-462b-815c-39d73f443f64/F1.large.jpg NEWS - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/0a09ec45-fdd7-4707-be88-81fc3de76713/Dori+Headshot.jpg NEWS - Congratulations to Dori on her award! Congratulations to Dori on being one of the newest endowed chairs at UMass Chan Medical School! She will hold the UMass Chan Medical School Chair in Biomedical Research I, generously funded by the UMass Memorial Health and UMass Foundation. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/4ca98e30-4e45-4bf4-9d3d-86a9c18d91f6/image002.jpg NEWS - Welcome Clarisse! The Schafer lab is lucky to have Clarisse Skende join our lab as a research associate! She is a recent graduate of John Hopkins and interested in attending medical school in the future. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1b84cf19-fcb1-42b5-b7ec-e03d9dd71264/IMG_5828.jpg NEWS - Summer outing! Schafer lab had fun on STEM day at Polar Park. Cheer on the Woo Sox! https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1721678686393-383SOK54YQJ2MAF40QU8/IMG_8081.jpg NEWS - Welcome Anna! Schafer was lucky to have Anna Aristarkhova join us as a MD/PhD student! https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/61f00cd9-60d0-41c3-98ba-755908cfcc10/Picture1.jpg NEWS - Congratulations to Jacob on his award! PhD candidate Jacob Stillman receives a F31 Ruth L. Kirschstein Predoctoral National Research Service Award for multiple sclerosis research. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/62f0f99a-af17-4689-8953-d22d7eb32d82/IMG_7130.jpg NEWS - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/87c9dbce-a8c3-4f0b-98f1-c96f9923dd25/IMG_3478.jpeg NEWS - Congratulation Philip for earning his MD/PhD degree! Congratulating Philip for earning his MD/PhD and receiving The Provost's Award and Catherine Miers Zurier Memorial Award in the process. You are a star! https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/677d06c7-9031-42f9-9adc-0b3c7eda9a87/IMG_5597.jpeg NEWS - Congratulations Becca and Pablo! Cheers to the recipients of the mentor award from the graduate school! https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/d77adb51-1352-4b52-9a8b-6f374b43d128/1-s2.0-S0959438824000394-gr1_lrg.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1717605553494-9AW43D9TNKTFUAORCU8J/IMG_6831.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1717605555042-FS9HBQ8R2T4B0Z7GP845/IMG_6825.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1717605554193-4RWTV402F7C5MUAVL5TZ/IMG_6827.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1717605552318-GI5R97ONRU33VSJME90S/IMG_6857.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1717605552214-CQQ57ML35VR4486EI3S9/IMG_6841.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1717606065364-P3MIZEBX0OKYMGN98FEA/IMG_7131.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/98482718-bf54-445d-b777-4d5c2cbc8ca8/IMG_6680.jpg NEWS - Congratulations to Melanie and Echo on passing their qualifying exam! Schafer lab celebrating with Melanie and Echo. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/0a09ec45-fdd7-4707-be88-81fc3de76713/Dori+Headshot.jpg NEWS - Congratulations to Dori! Congratulations to Dori for receiving the Mahoney Institute for Neurosciences Rising Star Award. Dr. Schafer helped delineate the mechanisms that propagate inflammation in neurodegenerative disease. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1569445407206-VID4P5TTFTEEQ1P618Y8/PAF_Headshot_Full.jpeg NEWS - Congratulations to Philip on his match! Congratulations to Philip Feinberg for matching at UMass Chan Medical School for Anesthesiology https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1694789815437-SL2HQEGD6ZRUVCCKKG0X/Melanie.JPG NEWS - Congratulations to Melanie on her award! Congratulations to Melanie for receiving a Transdisciplinary Training in Cardiovascular Research NHLBI T32. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1663967833653-0HIRDPSGUT82R7QDR1ZM/pat+headshot.jpg NEWS - Congratulations to Pat on his award! Congratulations to Pat for receiving a Marian Kies Memorial Award for his outstanding research conducted during graduate training from ASN! https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/e4cc12db-f4a5-46fb-934c-a466281fd51a/Picture1.jpg NEWS - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/a898be9e-2f5f-4a60-8e86-1519bc07b92f/pat+headshot.jpg NEWS - Congratulations to Pat on his award! Congratulations to Pat for receiving a National MS Society postdoctoral fellowship https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/8c097a6d-b5cd-4530-9d7e-d3c50cd1ee5f/IMG_7911.jpg NEWS - Winter holiday party Schafer lab celebrate Jacob and Francisco’s paper publication at Tree House winery. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/4a4509a0-d386-426f-92b7-812a0df29739/120623Beiter02_crop.JPG NEWS - Congratulations to Becca on her award! Congratulations to Becca for receiving a Ruth L. Kirschstein Postdoctoral Individual National Research Service Award (F32) from NINDS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1701205205410-CBOTICPGG7C6KA3Y1HNJ/IMG_5129.jpeg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1701205180844-MRBQF3XWSEPXD55QOEE4/IMG_5135.JPG NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1701205198442-S5ML5KSP6YANLPR83U9W/IMG_5130.jpeg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1701205531920-23WE5S0651VERG29AKC6/IMG_5172.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/9725c950-634e-4b5e-9c95-ef4feb339bc6/IMG_4976.jpg NEWS - Congratulations Jacob! Celebrating with the lab after Jacob and Francisco’s paper is accepted in Nature Communications. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/b1ca0721-a2aa-4d22-94f0-3092f3a18e6d/IMG_4568+2.JPG NEWS - Schafer Lab go apple picking at Nashoba Winery! https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/7e3b3934-54bb-45c0-af84-f46eeed9cd99/IMG_4832.jpeg NEWS - Congratulations Eva! Eva was recognized at the UMass Chan QE ceremony for passing her qualifying exam in March. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/d1dc49fd-9336-495f-9a81-5ede75ac8cc5/fx1_lrg.jpg NEWS - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/c1a60e19-83e5-41e2-a1d4-be18e77f8750/Woo+Sox.jpeg NEWS - Schafer Lab outing to cheer on the Woo Sox on STEM day at Polar Park. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/2ea3780b-9edc-4c63-bcef-35dc0aa04af1/cell+reports+photo.jpeg NEWS - Congratulations! Celebrating with the lab after Travis and Philip’s paper was accepted in Cell Reports. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/7ab12773-b0a8-41d2-80ae-3ccba981bc04/2023+lab+outing.jpg NEWS - Summer outing! The Schafer lab enjoyed an afternoon of minigolf and ice cream at Kimball Farms. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/f69e60cd-c96a-4b2a-94c2-a74a236e7f64/Duran-Laforet-Violeta.png NEWS - Congratulations to Violeta on her award! Violeta Durán Laforet was awarded the 2023 Faculty Award for Outstanding Contributions to Trainee Mentoring and Professional Advancement by a Postdoctoral Associate https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/5a8267a0-65fa-4ec6-8283-c3ec84f399e8/eva+QE.jpeg NEWS - Congratulations to Eva on passing her qualifying exam! https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/b2036f4b-6409-4f1a-a920-500b13c78af6/johana.png NEWS - Welcome Johana! The Schafer lab was lucky to have Johana Cela join us as a research associate this week. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/54aa035e-cf7a-4219-903b-984e38819f5f/lab+bday.jpeg NEWS - Happy Birthday! Jacob and Violeta happily share birthday cupcakes. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1668219213565-I47Q56CSRU86F2WAVS0O/image_50416129.JPG NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1668219213299-J2P65IQKA4G0GH77FD76/image_50444289.JPG NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1661051492129-K8UX02NAK9EHCOR1IA8F/-5361247309953446849.jpg NEWS - Congratulations to Philip Feinberg for completion of his PhD thesis and the publication of his research in JNeurosci! Follow the link below to read his work on “Elevated TNF-α Leads to Neural Circuit Instability in the Absence of Interferon Regulatory Factor 8” https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/4dfda32a-fdcc-4803-89fa-8fdaedb53499/sebastian+celebration.jpg NEWS - Celebrating postdoc Sebastian Werneburg’s forthcoming new position as an assistant professor at the University of Michigan! Stay tuned for more amazing science from Sebastian. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/89b8d9e5-5da6-4b5f-bef7-305c0a895562/Shannon+Farewell.jpg NEWS - Sadly wishing a fond farewell to Shannon Becker, our incomparable technician and lab manager Shannon is headed to Virginia to pursue her medical education. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/53084028-aaae-40b5-94d9-95f0fa83e7f0/brightfocus.jpg NEWS - Postdoc Violeta Durán Laforet was awarded a fellowship from the BrightFocus Foundation. Congratulations!! https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/6aa56590-21b5-489d-a5b2-ca2491b75737/francisco.jfif NEWS - Congratulations to Francisco Lopes on successfully defending his Master’s thesis from NOVA Medical School with the highest honors! Francisco did his Master’s thesis in the Schafer lab on microglia and immune memory https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1651461690738-JCRK7OBFVROWKE58OULA/Eva+Headshot.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1651461691066-1QJIXNF7IYS33WVBBFZS/TK_Photo.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/530b3259-6fa2-4e7b-9243-e60d19d505a2/violeta_website.jpg NEWS - Congratulations to Violeta Durán Laforet for receiving an Alzheimer’s Association International Research Fellowship Grant https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/148a4914-e765-4465-9190-21bbec9da1ad/Schafer+Lab+2021+Holiday+Party.jpg NEWS - Make it stand out Whatever it is, the way you tell your story online can make all the difference. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1620755255382-5YI37ETQY2ABQCIAZ6JA/jacob2.jpg NEWS - Congratulations! 2nd year PhD student Jacob Stillman won the poster prize at the UMass Chan Research Retreat https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1631280571906-I6DMD4WI3L3HR6Y9JN13/Lauren+goodbye1.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1631280572313-C9ODKSQTL1VZWBEPHBKD/Lauren+goodbye2.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1627578805977-LAI59CG8AQIWFBUPE8NZ/cake.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1627578185135-1EUUN2PIA9LRZVVJ67AW/Dr.+Gunner.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1627578185589-TQ2B2EQSQ111928047AB/Georgia+dunk.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1621542802478-2C2CCRNAALVSNX6QIDAI/Immunity.jpg NEWS - Werneburg et al. was by Immunity as one of the Best in Immunity 2020!!! https://info.cell.com/best-of-immunity-2020 https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1620755323166-A2E6JJ8IN8RW3VYSYJPK/Chun-Wei%252Bpic.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1620755255382-5YI37ETQY2ABQCIAZ6JA/jacob2.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1620755152291-XTM9QLII9U4RGOKDZO79/Leeyup_Chung.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1620755152319-V2AA8I148OMZQ58UNS0A/violeta%2Blab%2Bwebsite.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1598553499223-HJTTWYYEH1TGX1QYTN5X/erica+grad.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1596655559641-J8ZUHBK0E2O36PY5GSK5/jonathan%2Bgoing%2Baway.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1592923630576-QDMRKZBPU6FF29K41SGM/umassmednow+news+062320.png NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1592835304848-AXZJUO86YJG7HVE2JKS2/SFN-logo.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1592834905078-WOCOUXU80W8LKHP1OG1Z/neurosciene+scholars+program.png NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1588168710202-FXDJOM6ZYGZAIIUCPP8V/Picture1.png NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1584624160333-TFITGMLYZKMVAHPBA86J/Image%2Bfrom%2BiOS.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1582824638907-CKQCASYEMQO6YNF1XHT1/Sebastian%2BTubing.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1582824576611-XIX9BDBV686VT3HOCAOG/Casa%2BVallerta%2BDinner.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1582824498468-JK9QB0WMBWLX31PCIP7Q/Group+Tubing+Picture.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1579120475755-S85P3VLKG0YFDAQOEYEF/umassnow.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1577989242506-POGRF9ZIKKW45U7M6DZV/sebastian+graphical+abstract.jpg NEWS - Out now in Immunity! Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease Werneburg et al. Congratulations, Sebastian! https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1569445155077-DM30HXNJ2MDSVDQV6TA3/philip+AS+grant.png NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1564768153873-H74XUH3970QLZXGMJZDV/BBRFScientificCouncil2019+-+271.jpg NEWS - Congratulations to Dori on her 2019 Freedman Prize Honorable Mention from the Brain and Behavior Research Foundation! https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1564767780158-MLIP4W6TN076IO78LLMZ/image1.jpg NEWS - Interns present their data to the lab! 2019 summer undergraduate interns Tete Brenda Thomas and Meggan Mwangi spent 8-10 weeks in the Schafer laboratory working on microglia-related projects and presented their findings on July 25th. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1560833189152-OTG4Z7XYJGUBW2LD0DQH/Paper%2BScreenShot.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1559310837052-ALT9WG5LT3G7H63XHHL0/IMG_5482.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1557169785196-SON7A0NGSKW1ZTACJC8S/Screen+Shot+2019-05-06+at+3.07.43+PM.png NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1555682646473-VK5M5MX9TEW2Q5G864MV/ANya.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1548961993506-3FMOQTU7RQSGDD3SHG8I/IMG_2740.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1548962492371-MY1OFCQSJFNU0JSY9PAG/file.jpg NEWS - We https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1539964935402-RC6EOOI3P2E9VWQT9LNF/IMG_0024_2.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1539964348946-R628QG2IRIHGQE1WV7FO/IMG_0025.JPG NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1539964617641-F95TP2JDLZFZ3DMFTITN/IMG_1687+.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1537798472927-B7VMUZYCJO85LRH0EU2I/IMG_1629_2.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1534274009381-FQE4PLLDZMLLVHTVDADA/IMG_1803.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1529608419535-PTTC1JTQ6TSIFGM57QM2/IMG_0742.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1529608418952-T2LFXVUFKNNYS1FQWVOC/IMG_0016.JPG NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1529608420349-J7BIGECNPKUFRHBPUBPF/IMG_0768.JPG NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1529608418971-MW81NP1HGG6BBXX6J22P/IMG_0738.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1529608419622-GEADD826DGV6PY58T7LS/IMG_0743.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1529608420346-4XX5SFQ2EGRI7XUF4GYP/IMG_0758.JPG NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1529608420872-BHIO3PMX2BL2W4ZRLSDO/IMG_5547.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1529607992144-RGG7YOPI36FKQLTOVVP3/IMG_0757.JPG NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1529607909943-1XRTZ8X6JLFO1TPZ4CZR/IMG_0759.JPG NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1529607910433-KFBNHVVN4XS048R1SRT0/IMG_0760.JPG NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1522871375159-EK2RQFUGUS21V83HLOMS/IMG_0156.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1522871400958-P1Z79R8R10UFO099JJ3W/IMG_0157.jpg NEWS https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1516988897139-2ULHDK8T5OYAU4A3NW1Q/8CC20D24-087B-41C4-9344-27C9BBFD8001.jpeg NEWS Welcome Avery! 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Removal of whiskers (-whiskers) leads to decreased neural activity and corresponding loss of synapses in the barrel cortex (A) and microglial engulfment of synapses (yellow arrows, B). C. Blocking microglial engulfment in mice deficient in fractalkine receptor (CX3CR1 KO) or fractalkine ligand (CX3CL1 KO) signaling results in failure of synapses to be eliminated in the barrel cortex following whisker removal. D. We are using single-cell RNAseq approaches to dissect the cellular sources of molecules regulating microglial pruning of synapses and determine how these cell populations change with dampened neural activity following whisker removal. See also Gunner et al. Nat Neurosci 2019. https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1613423529200-U7LY8HINV78O9AX1FNEM/Blood%2Bvessels%2B1.jpg RESEARCH https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1613423306822-YE6VZEKHSOQTAUHF345B/Neonate+BV+video.gif RESEARCH Neonate https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1613423360049-T6QSAW8PYV32FD9TGS18/Adult+BV+video.gif RESEARCH Adult https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1613422869175-09TC1RLXVAAKKYJAYSWI/Blood%2Bvessels%2B2.jpg RESEARCH Left top panel, a juxtavascular microglia (green) in the neonate cortex during the first postnatal week. Right top panels, videos of live imaging of juxtavascular microglia in acute brain slices over 6 hrs. Juxtavascualar microglia are highly migratory along vessels in neonates (middle top panel) and stable in adults (right top panel). Bottom panel, 2-photon live imaging in awake, behaving adult mice demonstrates that juxtavascular microglia (green, arrowheads) are highly stable over 6 weeks of imaging. See Mondo et al. J. Neurosci 2020 https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1603897119139-2PC9PI9S1HR3YIXGGBP7/EAE+website.jpg RESEARCH Top panel, Synapse (immunostained with anti-VGluT2) loss in the human MS thalamus (left) and Iba+ putative microglia engulfment of presynaptic terminals (right, white arrows highlight engulfed material). This biology is recapitulated in a mouse model of inflammatory demeyleinating disease (mouse EAE). If we block microglial engulfment, we can prevent synapse loss (see Werneburg et al. Immunity 2020) https://www.schaferlabumms.com/publications daily 0.75 2025-08-25 https://www.schaferlabumms.com/alumni daily 0.75 2025-11-12 https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1ce5e174-1b9f-4907-b232-3f18709fd691/johana.jpg Alumni - Johana Lu (Cela) Lab manager https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1620755152319-V2AA8I148OMZQ58UNS0A/violeta%2Blab%2Bwebsite.jpg Alumni - Violeta Durán Laforet Postdoctoral Associate https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/a1ccb325-90bc-427a-9745-296819d5c8bd/IMG_0937.jpg Alumni - Eliana Bilsel Undergard intern https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/c1c39e29-00c7-45c9-ba76-9de2ffe51b31/031225Murphyfn01+%281%29.JPG Alumni - Rob Murphy Research Technician https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/25fe7100-2359-4ab9-9c6d-cd425103991d/Maggie+Boyle+Headshot.jpg Alumni - Maggie Boyle Research Technician https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/f9ea5f0d-11e3-4172-bf61-02732b767f5b/christina_hung.jpg Alumni - Christina Hung Research Technician https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/7be9fa86-709d-4fc4-9190-9f6701ac595a/Ciara+O%27Connor+Picture.jpg Alumni - Ciara O’Connor Research Technician https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1509484250175-745QEUEBZHPLQWEEHLE3/IMG_1323.JPG Alumni - Sebastian Werneburg Postdoctoral Associate https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/ab51777d-a733-4652-9e4a-2b28634da784/mqp+pic.jpg Alumni - Shannon Becker Research Technician https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/eea23ca6-1815-4c90-8a66-9ec2b2a3c638/Anya+Bio+Pic.jpg Alumni - Anya Song Graduate Student https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/4400f32e-8450-4d51-8740-17c00d4a901e/PAF_Headshot_Full.jpg Alumni - Philip Feinberg MD/PhD Student https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1583348319522-M72FXSJIC5IRR10DUOMB/FL+website+pic.jpg Alumni - Francisco Lopes Masters Student https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1620755152291-XTM9QLII9U4RGOKDZO79/Leeyup_Chung.jpg Alumni - Leeyup Chung Postdoctoral Associate https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/5ad1a57d-5ee7-476b-abe5-1f27c9840b5e/laurenwebsite2.jpg Alumni - Lauren Merritt Research Technician https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/bb2b37dc-888d-4e2a-b152-d5b1e899466c/GGunner%2BPicture.jpg Alumni - Georgia Gunner Graduate Student https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/0c027034-98df-466b-ac07-03d6c590c9d6/jonathan.jpg Alumni - Jonathan Jung Research Technician https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1578668653310-V49ID15H1B3QADTFUNLM/Cruz+prof+pic+headshot+%28002%29.jpg Alumni - Ivelisse Cruz Torres Postdoctoral Associate https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/2ce33f40-4825-4eea-8d78-a02efa2fe58d/erica+grad.jpg Alumni - Erica Mondo Graduate Student https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1509122134617-1EXWUDH3M2U79NGW7CT8/IMG_0118.JPG Alumni - Amanda Kautzman Postdoctoral Associate https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/4e5e8d0b-e591-4ce7-b3d8-58171e6248b9/yonca.jpg Alumni - Yonca Karadeniz Graduate Student https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/78a806a6-3c24-4260-a1c7-4410ddaa7926/Anoushka.jpg Alumni - Anoushka Lotun Research Technician https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/439d38d1-7217-4363-83e9-ac81a0e92bc1/Jeff.jpg Alumni - Jeffrey Frost Graduate Student https://images.squarespace-cdn.com/content/v1/59e66f67268b96bcf66e3f0e/1510064087499-FLJ67WK3QIPSXN9QLXBQ/Kasey.jpg Alumni - Kasey Johnson Postdoctoral Associate https://www.schaferlabumms.com/new-page-1 daily 0.75 2025-05-19